| Accession | HsInv0121 | Region of the inversion | chr11:1642775-1663993 |
| Status | Validated | Prediction type | Simple |
| Estimated Inversion Size | 20,169 bp | Supporting predictions | 2 |
| Inverted allele frequency | ND | Mechanism of origin | ND |
| Functional effect | Inverts a region within an intron of a gene | Breakpoint 1 | chr11:1642775-1643825 |
| Ancestral orientation | NA | Breakpoint 2 | chr11:1662943-1663993 |
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Human Polymorphic Inversion DataBase
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General information
- Region map
+ Predictions
| Description | Next generation sequencing and analysis by paired-end mapping of a Korean individual genome | ||||||||||||||
| Method | Paired-end mapping (PEM) | ||||||||||||||
| Name | |||||||
| Breakpoint 1 | chr11:1643225-1643375 | Breakpoint 2 | chr11:1663393-1663543 | ||||
| Individuals |
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| Description | Paired-end mapping of 3-kb fragments in an African and in a putatively European individual with some predictions validated by PCR, fiber-FISH or comparison with Celera assembly | ||||||||||||||||
| Method | Paired-end mapping (PEM) | ||||||||||||||||
| Name | |||||||||
| Breakpoint 1 | chr11:1647047-1647047 | Breakpoint 2 | chr11:1663209-1663209 | ||||||
| Individuals |
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+ Validation and genotyping
| Description | Paired-end mapping of 3-kb fragments in an African and in a putatively European individual with some predictions validated by PCR, fiber-FISH or comparison with Celera assembly | ||
| Method | Polymerase chain reaction (PCR) |
| Status | Validated |
+ Frequency
No frequency studied
+ Breakpoints
| Breakpoint 1 | chr11:1642775-1643825 | Breakpoint 2 | chr11:1662943-1663993 | |||||||||||||
| Definition method | Default informatic definition | |||||||||||||||
| Mechanism of origin |
ND
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| Flexibility | 9.8 | GC content | 0.62 | Stability | 2.07 |
| Position SD1 | Size (bp) | Position SD2 | Size (bp) | Identity | Relative orientation |
| chr11:1638692-1645264 | 6,573 | chr11:1661075-1668697 | 7,623 | 0.980 | Inverted |
+ Evolutionary history
| Ancestral allele | NA | Age | ND |
| Derived allele | NA | Origin | ND |
+ Orientation in other species
Not defined
+ Age
Not defined
+ Origin
Not defined
+ Functional effects
- MOB2
| Gene position | chr11:1447260-1742077 |
| Mechanism | Inverts a region within an intron of a gene |
+ Inversion phenotypical effects
Not defined
+ Report history
- 2015-02-23 10:14:59
| Breakpoint 1 | chr11:1642775-1643825 | Breakpoint 2 | chr11:1662943-1663993 |
| Assembly | hg18 | ||
| Definition method | Default informatic definition | ||
